death-inducing signaling complex (DISC)
GPTKB entity
Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:Fas_ligand
|
| gptkbp:composedOf |
gptkb:FADD
gptkb:procaspase-8 gptkb:Fas_receptor procaspase-10 |
| gptkbp:discoveredIn |
1995
|
| gptkbp:foundIn |
apoptosis pathway
|
| gptkbp:function |
initiates apoptosis
|
| gptkbp:hasComponent |
gptkb:death_effector_domain
death domain |
| https://www.w3.org/2000/01/rdf-schema#label |
death-inducing signaling complex (DISC)
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:relatedTo |
extrinsic apoptotic pathway
death receptor signaling |
| gptkbp:bfsParent |
gptkb:CD95
gptkb:caspase-8 |
| gptkbp:bfsLayer |
7
|