autoimmune lymphoproliferative syndrome
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:abbreviation |
gptkb:ALPS
|
| gptkbp:cause |
genetic disorder
|
| gptkbp:complication |
leukemia
|
| gptkbp:diagnostic_test |
gptkb:double_negative_T_cells
|
| gptkbp:firstDescribed |
1990s
|
| gptkbp:gene |
gptkb:FAS
gptkb:CASP10 gptkb:FASLG |
| gptkbp:hasOrphanetID |
ORPHA:46
|
| https://www.w3.org/2000/01/rdf-schema#label |
autoimmune lymphoproliferative syndrome
|
| gptkbp:ICD-10_code |
D89.8
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:MeSH_ID |
D020164
|
| gptkbp:OMIM |
601859
|
| gptkbp:onset |
childhood
|
| gptkbp:prevalence |
rare
|
| gptkbp:specialty |
immunology
hematology |
| gptkbp:symptom |
splenomegaly
lymphadenopathy autoimmune cytopenias |
| gptkbp:treatment |
gptkb:rituximab
gptkb:splenectomy immunosuppressive therapy corticosteroids |
| gptkbp:bfsParent |
gptkb:Fas
gptkb:Fas_receptor gptkb:CTLA-4 |
| gptkbp:bfsLayer |
6
|