Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
RNA molecule
|
| gptkbp:abbreviation |
small interfering RNA
|
| gptkbp:component |
gptkb:RNA-induced_silencing_complex
|
| gptkbp:discoveredBy |
gptkb:Andrew_Fire
gptkb:Craig_Mello |
| gptkbp:discoveredIn |
1998
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:fullName |
small interfering RNA
|
| gptkbp:function |
gptkb:RNA_interference
gene silencing |
| https://www.w3.org/2000/01/rdf-schema#label |
siRNA
|
| gptkbp:length |
20-25 nucleotides
|
| gptkbp:mechanismOfAction |
induces mRNA degradation
|
| gptkbp:medicalUse |
potential treatment for genetic diseases
|
| gptkbp:relatedTo |
gptkb:shRNA
non-coding RNA |
| gptkbp:structure |
double-stranded RNA
|
| gptkbp:target |
complementary mRNA
|
| gptkbp:usedFor |
post-transcriptional gene silencing
|
| gptkbp:usedIn |
therapeutic research
gene knockdown experiments |
| gptkbp:bfsParent |
gptkb:RNA_polymerase
gptkb:c-Myc gptkb:Dicer_enzyme |
| gptkbp:bfsLayer |
6
|