|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:MYC
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:binds
|
E-box DNA sequences
|
|
gptkbp:discoveredBy
|
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodes
|
gptkb:c-Myc_protein
|
|
gptkbp:Entrez_Gene_ID
|
4609
ENSG00000136997
|
|
gptkbp:formsHeterodimerWith
|
gptkb:MAX_protein
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
7553
|
|
gptkbp:homologInVirus
|
gptkb:v-Myc
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
proto-oncogene c-Myc
|
|
gptkbp:locatedOnChromosome
|
gptkb:8q24
|
|
gptkbp:mutationAssociatedWith
|
gptkb:neuroblastoma
gptkb:Burkitt_lymphoma
gptkb:cancer
colorectal cancer
multiple myeloma
translocation
amplification
|
|
gptkbp:OMIM
|
190080
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:overexpressedIn
|
tumorigenesis
|
|
gptkbp:proteinFamily
|
basic helix-loop-helix leucine zipper
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
metabolism
cellular senescence
angiogenesis
cell growth
protein synthesis
DNA replication
immune response
cell cycle
chromatin structure
cell adhesion
ribosome biogenesis
cellular proliferation
stem cell self-renewal
histone acetylation
|
|
gptkbp:target
|
microRNAs
ubiquitin-mediated degradation
|
|
gptkbp:UniProtID
|
P01106
|
|
gptkbp:bfsParent
|
gptkb:c-Myc
|
|
gptkbp:bfsLayer
|
6
|