Wingless-related integration site

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:Wnt
gptkbp:discoveredIn	gptkb:Drosophila_melanogaster
gptkbp:encodes	gptkb:Wnt_proteins
gptkbp:firstDescribed	1982
gptkbp:foundIn	animals
gptkbp:hasMember	gptkb:WNT1 gptkb:WNT10A gptkb:WNT10B gptkb:WNT11 gptkb:WNT16 gptkb:WNT2 gptkb:WNT3 gptkb:WNT4 gptkb:WNT5A gptkb:WNT5B gptkb:WNT6 gptkb:WNT7A gptkb:WNT7B gptkb:WNT8A gptkb:WNT8B gptkb:WNT9A gptkb:WNT9B
https://www.w3.org/2000/01/rdf-schema#label	Wingless-related integration site
gptkbp:involvedIn	gptkb:cancer cell proliferation embryonic development cell migration cell signaling cell fate determination
gptkbp:mutationAssociatedWith	gptkb:cancer gptkb:bone colorectal cancer melanoma developmental disorders
gptkbp:namedAfter	wingless phenotype in Drosophila
gptkbp:orthologIn	gptkb:C._elegans gptkb:zebrafish gptkb:Xenopus humans mice
gptkbp:pathway	canonical Wnt pathway non-canonical Wnt pathway
gptkbp:product	secreted glycoprotein
gptkbp:recipient	gptkb:Frizzled_family
gptkbp:regulates	gene expression cell polarity stem cell renewal
gptkbp:relatedTo	gptkb:APC_protein gptkb:Axin gptkb:Dishevelled_proteins gptkb:Frizzled_receptors gptkb:GSK-3β gptkb:Porcupine_protein gptkb:β-catenin
gptkbp:bfsParent	gptkb:WNT
gptkbp:bfsLayer	6