Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:cancer
colorectal cancer hepatocellular carcinoma |
| gptkbp:discoveredIn |
1998
|
| gptkbp:domain |
gptkb:DIX_domain
gptkb:RGS_domain coiled-coil domain |
| gptkbp:foundIn |
humans
mice other animals |
| gptkbp:function |
scaffold protein in Wnt signaling pathway
|
| gptkbp:gene |
gptkb:AXIN1
gptkb:AXIN2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Axin
|
| gptkbp:inhibitedBy |
gptkb:Wnt_signaling
|
| gptkbp:interactsWith |
gptkb:GSK-3β
gptkb:APC gptkb:β-catenin gptkb:CK1 |
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:orthologIn |
gptkb:Axin_in_Drosophila
PRY-1 in C. elegans |
| gptkbp:regulates |
β-catenin degradation
|
| gptkbp:bfsParent |
gptkb:Wnt_signaling_pathway
gptkb:Catenin_beta-1 |
| gptkbp:bfsLayer |
6
|