|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:p75NTR
gptkb:CD271
gptkb:nerve_growth_factor_receptor
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:schwannoma
melanoma
|
|
gptkbp:binds
|
gptkb:nerve_growth_factor
gptkb:brain-derived_neurotrophic_factor
gptkb:neurotrophin-3
gptkb:neurotrophin-4
|
|
gptkbp:encodes
|
gptkb:NGFR_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000064300
4804
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
immune system
|
|
gptkbp:firstDescribed
|
1986
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasDeathDomain
|
true
|
|
gptkbp:hasParalog
|
gptkb:TNFRSF1A
gptkb:TNFRSF1B
|
|
gptkbp:HGNC_ID
|
7808
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TNFRSF16
|
|
gptkbp:involvedIn
|
gptkb:neurotrophin_signaling_pathway
neuronal apoptosis
neuronal survival
|
|
gptkbp:length
|
427 amino acids
|
|
gptkbp:ligand
|
neurotrophins
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17
gptkb:17q21.33
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:molecularWeight
|
45 kDa
|
|
gptkbp:OMIM
|
162010
|
|
gptkbp:orthologInMouse
|
gptkb:Tnfrsf16
|
|
gptkbp:orthologInZebrafish
|
tnfrsf16a
|
|
gptkbp:product
|
gptkb:p75_neurotrophin_receptor
|
|
gptkbp:proteinFamily
|
gptkb:TNFRSF
|
|
gptkbp:regulates
|
axon growth
neurite outgrowth
cell death
|
|
gptkbp:significance
|
gptkb:cancer
neurodegenerative diseases
nerve injury
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
gptkb:P08138
|
|
gptkbp:bfsParent
|
gptkb:NGFR
gptkb:NGFR_gene
gptkb:p75_neurotrophin_receptor
|
|
gptkbp:bfsLayer
|
7
|