gptkbp:instanceOf
|
gptkb:protein
growth factor
|
gptkbp:abbreviation
|
gptkb:NGF
|
gptkbp:category
|
biological factor
growth factor
signaling molecule
|
gptkbp:discoveredBy
|
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen
|
gptkbp:discoveredIn
|
1950s
|
gptkbp:function
|
differentiation of neurons
promotes survival of neurons
stimulates growth of nerve cells
|
gptkbp:gene
|
NGF gene
|
https://www.w3.org/2000/01/rdf-schema#label
|
nerve growth factor
|
gptkbp:locatedOnChromosome
|
gptkb:1p13.1
|
gptkbp:medicalUse
|
investigated for corneal ulcers
investigated for neurodegenerative disorders
investigated for peripheral neuropathy
|
gptkbp:molecularWeight
|
26 kDa
|
gptkbp:NobelPrizeYear
|
gptkb:1986_Nobel_Prize_in_Physiology_or_Medicine
|
gptkbp:recipient
|
gptkb:TrkA
gptkb:p75NTR
|
gptkbp:relatedTo
|
gptkb:Alzheimer's_disease
gptkb:brain-derived_neurotrophic_factor
neurodegenerative diseases
neurotrophin family
pain modulation
|
gptkbp:species
|
found in humans
found in mice
found in other mammals
|
gptkbp:structure
|
homodimer
polypeptide
|
gptkbp:UniProtID
|
gptkb:P01138
|
gptkbp:bfsParent
|
gptkb:Rita_Levi-Montalcini
|
gptkbp:bfsLayer
|
4
|