nerve growth factor

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:protein
growth factor
gptkbp:abbreviation gptkb:NGF
gptkbp:category biological factor
growth factor
signaling molecule
gptkbp:discoveredBy gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen
gptkbp:discoveredIn 1950s
gptkbp:function differentiation of neurons
promotes survival of neurons
stimulates growth of nerve cells
gptkbp:gene NGF gene
https://www.w3.org/2000/01/rdf-schema#label nerve growth factor
gptkbp:locatedOnChromosome gptkb:1p13.1
gptkbp:medicalUse investigated for corneal ulcers
investigated for neurodegenerative disorders
investigated for peripheral neuropathy
gptkbp:molecularWeight 26 kDa
gptkbp:NobelPrizeYear gptkb:1986_Nobel_Prize_in_Physiology_or_Medicine
gptkbp:recipient gptkb:TrkA
gptkb:p75NTR
gptkbp:relatedTo gptkb:Alzheimer's_disease
gptkb:brain-derived_neurotrophic_factor
neurodegenerative diseases
neurotrophin family
pain modulation
gptkbp:species found in humans
found in mice
found in other mammals
gptkbp:structure homodimer
polypeptide
gptkbp:UniProtID gptkb:P01138
gptkbp:bfsParent gptkb:Rita_Levi-Montalcini
gptkbp:bfsLayer 4