|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:p75NTR
gptkb:CD271
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
transmembrane signaling receptor activity
neurotrophin receptor activity
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
melanoma cells
|
|
gptkbp:externalResource
|
https://www.uniprot.org/uniprot/P08138
https://www.genecards.org/cgi-bin/carddisp.pl?gene=NGFR
|
|
gptkbp:fullName
|
Nerve growth factor receptor
|
|
gptkbp:function
|
binds nerve growth factor (NGF)
mediates neuronal survival and apoptosis
|
|
gptkbp:gene
|
gptkb:NGFR
|
|
gptkbp:HGNC_ID
|
7808
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NGFR protein
|
|
gptkbp:interactsWith
|
gptkb:NGF
gptkb:BDNF
gptkb:NT-3
gptkb:NT-4
gptkb:TRADD
Sortilin
|
|
gptkbp:length
|
427 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q21.33
|
|
gptkbp:location
|
gptkb:endosome
gptkb:cell_membrane
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:role
|
axon growth
neuronal differentiation
apoptosis regulation
|
|
gptkbp:structure
|
contains cysteine-rich domains
|
|
gptkbp:UniProtID
|
gptkb:P08138
|
|
gptkbp:bfsParent
|
gptkb:TNFRSF16
|
|
gptkbp:bfsLayer
|
8
|