|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:p75NTR
gptkb:CD271
gptkb:TNFRSF16
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:schwannoma
melanoma
|
|
gptkbp:cellSurfaceMarker
|
gptkb:CD271
|
|
gptkbp:discoveredIn
|
1986
|
|
gptkbp:encodes
|
gptkb:p75_neurotrophin_receptor
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000064300
4804
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
melanoma cells
mesenchymal stem cells
|
|
gptkbp:fullName
|
gptkb:nerve_growth_factor_receptor
|
|
gptkbp:function
|
binds nerve growth factor (NGF)
regulates neuronal survival and apoptosis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
7808
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NGFR
|
|
gptkbp:interactsWith
|
gptkb:NGF
gptkb:BDNF
gptkb:NT-3
gptkb:NT-4
|
|
gptkbp:length
|
427 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q21.33
|
|
gptkbp:marking
|
melanoma stem cells
mesenchymal stem cells
neural crest stem cells
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:molecularWeight
|
45 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:congenital_insensitivity_to_pain
|
|
gptkbp:OMIM
|
162010
|
|
gptkbp:orthologInMouse
|
gptkb:Ngfr
|
|
gptkbp:product
|
cell surface receptor
|
|
gptkbp:regulates
|
gptkb:synaptic_plasticity
cell migration
inflammation
axon growth
myelination
neuronal differentiation
cell adhesion
cell death
|
|
gptkbp:structure
|
contains cysteine-rich domains
contains death domain
|
|
gptkbp:UniProtID
|
gptkb:P08138
|
|
gptkbp:bfsParent
|
gptkb:p75NTR
|
|
gptkbp:bfsLayer
|
6
|