|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:p75NTR
gptkb:NGFR
|
|
gptkbp:associatedWith
|
gptkb:neuroblastoma
gptkb:Alzheimer's_disease
melanoma
|
|
gptkbp:binds
|
gptkb:neurotrophin-3_(NT-3)
gptkb:brain-derived_neurotrophic_factor_(BDNF)
gptkb:nerve_growth_factor_(NGF)
gptkb:neurotrophin-4_(NT-4)
|
|
gptkbp:cellSurfaceMarker
|
yes
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:NGFR_gene
|
|
gptkbp:Entrez_Gene_ID
|
4804
|
|
gptkbp:expressedIn
|
gptkb:oligodendrocytes
development
central nervous system
peripheral nervous system
neurons
Schwann cells
astrocytes
melanoma cells
mesenchymal stem cells
injury response
|
|
gptkbp:function
|
gptkb:nerve_growth_factor_receptor
apoptosis
regulation of neuronal survival
|
|
gptkbp:HGNC_ID
|
7808
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD271
|
|
gptkbp:interactsWith
|
gptkb:TrkA
gptkb:TrkB
gptkb:TrkC
gptkb:sortilin
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q21.33
|
|
gptkbp:marking
|
melanoma stem cells
mesenchymal stem cells
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:molecularWeight
|
75 kDa
|
|
gptkbp:OMIM
|
162010
|
|
gptkbp:regulates
|
cell survival
neurite outgrowth
cell death
|
|
gptkbp:structureType
|
transmembrane glycoprotein
|
|
gptkbp:UniProtID
|
gptkb:P08138
|
|
gptkbp:usedIn
|
cancer research
stem cell isolation
|
|
gptkbp:bfsParent
|
gptkb:NGFR
gptkb:NGFR_gene
gptkb:p75_neurotrophin_receptor
|
|
gptkbp:bfsLayer
|
7
|