T-cell receptor signaling pathway
GPTKB entity
Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
cell differentiation
cell proliferation cytokine production T-cell activation |
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
autoimmune diseases immunodeficiency |
| gptkbp:encoded_in |
KEGG pathway hsa04660
|
| https://www.w3.org/2000/01/rdf-schema#label |
T-cell receptor signaling pathway
|
| gptkbp:involves |
gptkb:MAPK_pathway
gptkb:NFAT gptkb:ZAP-70 gptkb:LAT gptkb:T-cell_receptor gptkb:PI3K_pathway gptkb:CD3_complex gptkb:Lck gptkb:NF-κB gptkb:AP-1 gptkb:PLC-gamma1 gptkb:SLP-76 calcium signaling ITAMs |
| gptkbp:launched |
antigen recognition
|
| gptkbp:occurredIn |
T lymphocytes
|
| gptkbp:part_of |
adaptive immune response
|
| gptkbp:regulates |
gptkb:CTLA-4
gptkb:PD-1 co-stimulatory molecules |
| gptkbp:studiedBy |
immunology
|
| gptkbp:bfsParent |
gptkb:TEC_tyrosine_kinase
gptkb:Hematopoietic_Progenitor_Kinase |
| gptkbp:bfsLayer |
7
|