|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
immunodeficiency
autoimmune disease
chronic lymphocytic leukemia
|
|
gptkbp:discoveredBy
|
gptkb:Arthur_Weiss
John C. Cambier
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:domain
|
kinase domain
SH2 domain
|
|
gptkbp:encodedBy
|
ZAP70 gene
|
|
gptkbp:enzymeCommissionNumber
|
2.7.10.2
|
|
gptkbp:expressedIn
|
gptkb:NK_cells
gptkb:T_cells
|
|
gptkbp:fullName
|
Zeta-chain-associated protein kinase 70
|
|
gptkbp:function
|
gptkb:receptor_tyrosine_kinase
T-cell receptor signaling
|
|
gptkbp:gene
|
gptkb:ZAP70
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ZAP-70
|
|
gptkbp:locatedOnChromosome
|
2q12
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
70 kDa
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
|
|
gptkbp:OMIM
|
176947
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Zap70
|
|
gptkbp:PDB
|
1U59
|
|
gptkbp:phosphorylates
|
gptkb:LAT
gptkb:SLP-76
|
|
gptkbp:UniProtID
|
P43403
|
|
gptkbp:bfsParent
|
gptkb:small_lymphocytic_lymphoma
|
|
gptkbp:bfsLayer
|
6
|