|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:MST1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
immunodeficiency
|
|
gptkbp:discoveredBy
|
Creasy et al.
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
STK4 protein
|
|
gptkbp:Entrez_Gene_ID
|
6789
|
|
gptkbp:enzymeClassification
|
EC 2.7.11.1
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:Serine/threonine-protein_kinase_4
|
|
gptkbp:function
|
gptkb:Hippo_signaling_pathway
regulation of apoptosis
cell cycle control
|
|
gptkbp:gene
|
gptkb:STK4
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:11415
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STK4
|
|
gptkbp:interactsWith
|
gptkb:SAV1
gptkb:BCL2L11
gptkb:RASSF1
MOB1A
MOB1B
|
|
gptkbp:length
|
487
|
|
gptkbp:locatedOnChromosome
|
20q13.12
|
|
gptkbp:molecularWeight
|
56 kDa
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
|
|
gptkbp:OMIM
|
604664
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Stk4
|
|
gptkbp:PDB
|
5B5W
5B5X
5B5Y
|
|
gptkbp:phosphorylates
|
gptkb:FOXO1
gptkb:FOXO3
gptkb:YAP1
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
tumor suppression
organ size
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
mitochondria
|
|
gptkbp:UniProtID
|
gptkb:Q13043
|
|
gptkbp:bfsParent
|
gptkb:MST1
|
|
gptkbp:bfsLayer
|
8
|