|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RASSF1A
RASSF1B
RASSF1C
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
apoptosis
cell cycle regulation
tumor suppression
|
|
gptkbp:downregulatedIn
|
gptkb:cancer
colorectal cancer
liver cancer
prostate cancer
|
|
gptkbp:encodes
|
RASSF1 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000104904
11186
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:firstDescribed
|
2000
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
Ras association domain family member 1
|
|
gptkbp:hasIsoform
|
gptkb:RASSF1A
RASSF1C
|
|
gptkbp:hasPromoterMethylation
|
frequent in cancers
|
|
gptkbp:HGNC_ID
|
HGNC:9887
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RASSF1
|
|
gptkbp:interactsWith
|
gptkb:MST1
gptkb:MOAP1
gptkb:MST2
microtubules
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_3
3p21.3
|
|
gptkbp:methylationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:methylationLeadsTo
|
gene silencing
|
|
gptkbp:OMIM
|
605082
|
|
gptkbp:orthologInMouse
|
Rassf1
|
|
gptkbp:regulates
|
apoptosis
cell division
microtubule stability
|
|
gptkbp:tumorSuppressorGene
|
true
|
|
gptkbp:UniProtID
|
Q9NS23
|
|
gptkbp:bfsParent
|
gptkb:3265_(HRAS)
gptkb:KEGG:_hsa04014
gptkb:P01112_(HRAS)
|
|
gptkbp:bfsLayer
|
6
|