Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:connectsTo |
developmental biology
mechanotransduction cell contact inhibition |
| gptkbp:conservedIn |
gptkb:metazoans
|
| gptkbp:controls |
cell fate
tissue homeostasis |
| gptkbp:discoveredBy |
gptkb:Drosophila_melanogaster
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
organ overgrowth |
| https://www.w3.org/2000/01/rdf-schema#label |
Hippo signaling pathway
|
| gptkbp:inhibitedBy |
TAZ nuclear localization
YAP nuclear localization |
| gptkbp:involves |
gptkb:MST1
gptkb:LATS1 gptkb:LATS2 gptkb:SAV1 gptkb:YAP gptkb:NF2 gptkb:TAZ gptkb:MST2 TEAD transcription factors |
| gptkbp:KEGGID |
hsa04390
|
| gptkbp:namedAfter |
Hippo gene
|
| gptkbp:phosphorylates |
gptkb:YAP
gptkb:TAZ |
| gptkbp:regulates |
apoptosis
cell proliferation organ size stem cell self-renewal |
| gptkbp:bfsParent |
gptkb:RASSF5
gptkb:RASSF_proteins |
| gptkbp:bfsLayer |
7
|