|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:FKHR
gptkb:FKHRL1
gptkb:FOXO1A
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:diabetes_mellitus
gptkb:rhabdomyosarcoma
|
|
gptkbp:encodes
|
gptkb:FOXO1_protein
|
|
gptkbp:Entrez_Gene_ID
|
2308
ENSG00000150907
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
liver
adipose tissue
pancreas
|
|
gptkbp:formsFusionGene
|
gptkb:PAX3-FOXO1
gptkb:PAX7-FOXO1
|
|
gptkbp:fullName
|
gptkb:Forkhead_box_protein_O1
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
HGNC:3819
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FOXO1
|
|
gptkbp:locatedOnChromosome
|
13q14.11
|
|
gptkbp:memberOf
|
gptkb:FOXO_subfamily
forkhead family of transcription factors
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Foxo1
|
|
gptkbp:phosphorylates
|
gptkb:AKT1
gptkb:SGK
|
|
gptkbp:phosphorylationEffect
|
inactivation
nuclear export
|
|
gptkbp:regulates
|
apoptosis
DNA repair
lipid metabolism
angiogenesis
muscle atrophy
glucose metabolism
immune response
oxidative phosphorylation
cell cycle
autophagy
oxidative stress response
inflammatory response
insulin sensitivity
insulin signaling pathway
glycogenolysis
adipogenesis
cellular differentiation
gluconeogenesis
cellular proliferation
|
|
gptkbp:translocationPartner
|
gptkb:PAX3
gptkb:PAX7
|
|
gptkbp:UniProtID
|
Q12778
|
|
gptkbp:bfsParent
|
gptkb:AKT1
gptkb:PAX3-FOXO1_fusion
gptkb:PAX7-FOXO1_fusion
gptkb:FOXO_transcription_factors
|
|
gptkbp:bfsLayer
|
6
|