Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:activatedBy |
oxidative stress
|
| gptkbp:alias |
gptkb:FKHRL1
gptkb:FOXO3A AF6q21 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:diabetes human longevity |
| gptkbp:encodes |
gptkb:FOXO3_protein
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000118689
2309 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
gptkb:Forkhead_box_O3
|
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
gptkb:HGNC:3821
|
| https://www.w3.org/2000/01/rdf-schema#label |
FOXO3
|
| gptkbp:inhibitedBy |
insulin signaling
|
| gptkbp:locatedOnChromosome |
gptkb:6q21
|
| gptkbp:memberOf |
gptkb:FOXO_subfamily
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Foxo3
|
| gptkbp:phosphorylates |
gptkb:AKT1
|
| gptkbp:regulates |
apoptosis
longevity DNA repair cell cycle oxidative stress response |
| gptkbp:UniProtID |
O43524
|
| gptkbp:bfsParent |
gptkb:AKT1
gptkb:AMPK_pathway gptkb:FOXO_transcription_factors |
| gptkbp:bfsLayer |
6
|