|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
WW45
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:component
|
Hippo signaling complex
|
|
gptkbp:discoveredBy
|
Harvey laboratory
|
|
gptkbp:domain
|
gptkb:WW_domain
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000119682
60485
|
|
gptkbp:fullName
|
Salvador family WW domain-containing protein 1
|
|
gptkbp:function
|
tumor suppressor
protein binding
regulation of Hippo signaling pathway
|
|
gptkbp:gene
|
gptkb:SAV1
|
|
gptkbp:GOProcess
|
negative regulation of cell proliferation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SAV1
|
|
gptkbp:interactsWith
|
gptkb:MST1
gptkb:LATS1
gptkb:LATS2
gptkb:MST2
|
|
gptkbp:length
|
383
|
|
gptkbp:locatedOnChromosome
|
14q22.1
|
|
gptkbp:molecularWeight
|
45 kDa
|
|
gptkbp:mutationAssociatedWith
|
mesothelioma
renal cell carcinoma
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9H4B6
|
|
gptkbp:bfsParent
|
gptkb:MST1
gptkb:Hippo_signaling_pathway
gptkb:MST2
|
|
gptkbp:bfsLayer
|
8
|