p66Shc

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName SHC-transforming protein 1 isoform p66
gptkbp:discoveredBy Pier Giuseppe Pelicci
gptkbp:discoveredIn 1999
gptkbp:domain SH2 domain
PTB domain
CH1 domain
gptkbp:encodedBy gptkb:SHC1_gene
gptkbp:function signal transduction
regulation of apoptosis
regulation of oxidative stress response
gptkbp:hasIsoform Shc1 protein
https://www.w3.org/2000/01/rdf-schema#label p66Shc
gptkbp:involvedIn gptkb:cardiovascular_disease
gptkb:diabetes
aging
gptkbp:locale gptkb:cytoplasm
mitochondria
gptkbp:molecularWeight 66 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:phosphorylates Ser36
gptkbp:postTranslationalModification phosphorylation
acetylation
gptkbp:regulates reactive oxygen species production
gptkbp:species gptkb:human
gptkbp:bfsParent gptkb:SHC1
gptkbp:bfsLayer 7