|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodevelopmental disorders
synaptic function
focal adhesions
|
|
gptkbp:biologicalProcess
|
ARF GTPase-activating protein activity
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
synapse
focal adhesion
|
|
gptkbp:discoveredBy
|
Premont RT et al.
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodes
|
GIT1 protein
|
|
gptkbp:Entrez_Gene_ID
|
28964
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
brain
heart
|
|
gptkbp:fullName
|
G protein-coupled receptor kinase interactor 1
|
|
gptkbp:function
|
signal transduction
regulation of cell migration
regulation of cytoskeleton
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GIT1
|
|
gptkbp:interactsWith
|
gptkb:PAK1
gptkb:paxillin
ARHGEF6
ARHGEF7
G protein-coupled receptor kinases (GRKs)
PIX proteins
beta-PIX
|
|
gptkbp:locatedOnChromosome
|
17p11.2
|
|
gptkbp:OMIM
|
605890
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Git1
|
|
gptkbp:UniProtID
|
gptkb:Q9Y2X7
|
|
gptkbp:bfsParent
|
gptkb:17q11.2
gptkb:PAK1
gptkb:Focal_adhesion_kinase
gptkb:CDC42
gptkb:Rac1
|
|
gptkbp:bfsLayer
|
7
|