| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:enzyme
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:activeSiteContains
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Amino acid residues
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:alsoKnownAs
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Protease
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:catalyzes
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Hydrolysis of peptide bonds
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:class
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Endopeptidase
                                        
                                         
                                    
                                        
                                            gptkb:Exopeptidase
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:cofactor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Metal ions (for metalloproteases)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:EC_number
                                    
                                 | 
                                
                                    
                                        
                                            
                                            3.4.-.-
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:example
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Caspase
                                        
                                         
                                    
                                        
                                            gptkb:Chymotrypsin
                                        
                                         
                                    
                                        
                                            gptkb:Thrombin
                                        
                                         
                                    
                                        
                                            gptkb:Proteasome
                                        
                                         
                                    
                                        
                                            gptkb:Aminopeptidase
                                        
                                         
                                    
                                        
                                            gptkb:Aspartic_protease
                                        
                                         
                                    
                                        
                                            gptkb:Carboxypeptidase
                                        
                                         
                                    
                                        
                                            gptkb:Cathepsin
                                        
                                         
                                    
                                        
                                            gptkb:Cysteine_protease
                                        
                                         
                                    
                                        
                                            gptkb:Dipeptidyl_peptidase
                                        
                                         
                                    
                                        
                                            gptkb:Glutamic_protease
                                        
                                         
                                    
                                        
                                            gptkb:Metalloprotease
                                        
                                         
                                    
                                        
                                            gptkb:Papain
                                        
                                         
                                    
                                        
                                            gptkb:Renin
                                        
                                         
                                    
                                        
                                            gptkb:Serine_protease
                                        
                                         
                                    
                                        
                                            gptkb:Threonine_protease
                                        
                                         
                                    
                                        
                                            
                                            Elastase
                                        
                                        
                                         
                                    
                                        
                                            
                                            Pepsin
                                        
                                        
                                         
                                    
                                        
                                            
                                            Trypsin
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:foundIn
                                    
                                 | 
                                
                                    
                                        
                                            
                                            All living organisms
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:function
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Protein catabolism
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:GO_term
                                    
                                 | 
                                
                                    
                                        
                                            
                                            GO:0008233
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:inhibitedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Protease inhibitors
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:medicalUse
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Antiviral therapy
                                        
                                        
                                         
                                    
                                        
                                            
                                            Blood clotting regulation
                                        
                                        
                                         
                                    
                                        
                                            
                                            Cancer therapy
                                        
                                        
                                         
                                    
                                        
                                            
                                            Treatment of digestive disorders
                                        
                                        
                                         
                                    
                                        
                                            
                                            Wound healing
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:presentIn
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Eukaryotes
                                        
                                         
                                    
                                        
                                            gptkb:Archaea
                                        
                                         
                                    
                                        
                                            gptkb:Bacteria
                                        
                                         
                                    
                                        
                                            
                                            Viruses
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:requires
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Digestion
                                        
                                        
                                         
                                    
                                        
                                            
                                            Immune response
                                        
                                        
                                         
                                    
                                        
                                            
                                            Cellular regulation
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:role
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Apoptosis
                                        
                                        
                                         
                                    
                                        
                                            
                                            Hormone activation
                                        
                                        
                                         
                                    
                                        
                                            
                                            Immune defense
                                        
                                        
                                         
                                    
                                        
                                            
                                            Protein turnover
                                        
                                        
                                         
                                    
                                        
                                            
                                            Signal peptide processing
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:structure
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:protein
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Enzymes
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            6
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            Peptidase
                                        
                                        
                                         
                                    
                                 |