|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activeSiteContains
|
Amino acid residues
|
|
gptkbp:alsoKnownAs
|
Protease
|
|
gptkbp:catalyzes
|
Hydrolysis of peptide bonds
|
|
gptkbp:class
|
gptkb:Endopeptidase
gptkb:Exopeptidase
|
|
gptkbp:cofactor
|
Metal ions (for metalloproteases)
|
|
gptkbp:EC_number
|
3.4.-.-
|
|
gptkbp:example
|
gptkb:Caspase
gptkb:Chymotrypsin
gptkb:Thrombin
gptkb:Proteasome
gptkb:Aminopeptidase
gptkb:Aspartic_protease
gptkb:Carboxypeptidase
gptkb:Cathepsin
gptkb:Cysteine_protease
gptkb:Dipeptidyl_peptidase
gptkb:Glutamic_protease
gptkb:Metalloprotease
gptkb:Papain
gptkb:Renin
gptkb:Serine_protease
gptkb:Threonine_protease
Elastase
Pepsin
Trypsin
|
|
gptkbp:foundIn
|
All living organisms
|
|
gptkbp:function
|
Protein catabolism
|
|
gptkbp:GO_term
|
GO:0008233
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Peptidase
|
|
gptkbp:inhibitedBy
|
Protease inhibitors
|
|
gptkbp:medicalUse
|
Antiviral therapy
Blood clotting regulation
Cancer therapy
Treatment of digestive disorders
Wound healing
|
|
gptkbp:presentIn
|
gptkb:Eukaryotes
gptkb:Bacteria
Archaea
Viruses
|
|
gptkbp:requires
|
Digestion
Immune response
Cellular regulation
|
|
gptkbp:role
|
Apoptosis
Hormone activation
Immune defense
Protein turnover
Signal peptide processing
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|