Statements (135)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
CYPIA2
Cytochrome P450DB1 P450-C |
| gptkbp:associatedWith |
drug metabolism
cancer susceptibility drug toxicity xenobiotic metabolism caffeine metabolism caffeine sensitivity |
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:ensembl |
ENSP00000261456
|
| gptkbp:Entrez_Gene_ID |
1544
|
| gptkbp:enzymeCommissionNumber |
1.14.14.1
|
| gptkbp:function |
Monooxygenase involved in drug metabolism
|
| gptkbp:gene |
gptkb:CYP1A2
|
| gptkbp:hasPolymorphism |
present
|
| https://www.w3.org/2000/01/rdf-schema#label |
P07347
|
| gptkbp:locatedOnChromosome |
15
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
|
| gptkbp:molecularWeight |
57910 Da
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
drug metabolism - cytochrome P450
metabolism of xenobiotics by cytochrome P450 |
| gptkbp:PDB |
gptkb:2HIU
2HI4 2HI5 2HI6 2HI7 2HI8 2HI9 2HIA 2HIB 2HIC 2HID 2HIE 2HIF 2HIG 2HIH 2HII 2HIJ 2HIK 2HIL 2HIM 2HIN 2HIO 2HIP 2HIQ 2HIR 2HIS 2HIT 2HIV 2HIW 2HIX 2HIY 2HIZ 2HJ0 2HJ1 2HJ2 2HJ3 2HJ4 2HJ5 2HJ6 2HJ7 2HJ8 2HJ9 2HJA 2HJB 2HJC 2HJD 2HJE 2HJF 2HJG 2HJH 2HJI 2HJJ 2HJK 2HJL 2HJM 2HJN 2HJO 2HJP 2HJQ 2HJR 2HJS 2HJT 2HJU 2HJV 2HJW 2HJX 2HJY 2HJZ |
| gptkbp:protein_name |
Cytochrome P450 1A2
|
| gptkbp:RefSeq |
NP_000755.2
|
| gptkbp:sequence |
515
|
| gptkbp:substrate |
gptkb:fluvoxamine
gptkb:theophylline gptkb:warfarin gptkb:tacrine gptkb:omeprazole gptkb:lidocaine gptkb:aflatoxin_B1 gptkb:estradiol gptkb:carbamazepine gptkb:melatonin gptkb:amitriptyline gptkb:imipramine gptkb:clozapine gptkb:duloxetine gptkb:olanzapine gptkb:zolpidem gptkb:tizanidine gptkb:rasagiline gptkb:clomipramine caffeine propranolol acetaminophen phenacetin phenobarbital aniline mexiletine benzo[a]pyrene 2-acetylaminofluorene 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline 2-amino-3,4-dimethylimidazo[4,5-f]quinoline 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline 2-amino-3-methyl-9H-pyrido[2,3-b]indole 2-amino-3-methylimidazo[4,5-f]quinoline 4-aminobiphenyl 2-amino-1,6-dimethylfuro[3,2-e]imidazo[4,5-b]pyridine |
| gptkbp:tissue_specificity |
liver
|
| gptkbp:UniProtID |
gptkb:P07347
|
| gptkbp:bfsParent |
gptkb:FUT1_gene
|
| gptkbp:bfsLayer |
7
|