gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:protein
macrocycle
|
gptkbp:alternativeName
|
blood_type
heme
hemoglobin_variant
hemoglobinopathy
porphyrin
red_blood_cell
|
gptkbp:associatedWith
|
gptkb:sickle_cell_anemia
gptkb:anemia
|
gptkbp:binds
|
oxygen
carbon dioxide
carbon monoxide
|
gptkbp:CASNumber
|
101-60-0
|
gptkbp:class
|
heterocycle
aromatic compound
|
gptkbp:cofactor
|
heme group
|
gptkbp:color
|
red
deep red to purple
|
gptkbp:contains
|
iron
|
gptkbp:containsElement
|
carbon
hydrogen
nitrogen
|
gptkbp:discoveredBy
|
gptkb:Hans_Fischer
gptkb:Friedrich_Ludwig_Hünefeld
|
gptkbp:discoveredIn
|
1840
|
gptkbp:EC_number
|
none
|
gptkbp:encodedBy
|
gptkb:HBA1_gene
gptkb:HBA2_gene
gptkb:HBB_gene
|
gptkbp:foundIn
|
gptkb:cytochromes
gptkb:myoglobin
hemoglobin
red blood cells
Chlorophyll
|
gptkbp:function
|
oxygen transport
|
gptkbp:hasAbsorptionMaximum
|
Soret band (around 400 nm)
|
gptkbp:hasBiologicalActivity
|
photosynthesis
oxygen transport
electron transfer
|
gptkbp:hasCoreCity
|
tetrapyrrole ring
|
gptkbp:hasDerivatives
|
gptkb:protoporphyrin_IX
coproporphyrin
uroporphyrin
mesoporphyrin
|
gptkbp:hasIsoform
|
gptkb:adult_hemoglobin
gptkb:fetal_hemoglobin
gptkb:hemoglobin_A
gptkb:hemoglobin_C
gptkb:hemoglobin_E
gptkb:hemoglobin_S
|
gptkbp:hasMolecularFormula
|
C2952H4664N812O832S8Fe4
C20H14N4
|
gptkbp:hasQuaternaryStructure
|
tetramer
|
gptkbp:hasSMILES
|
C1=CC2=CC3=CC=C(N3)C=C4C=CC(=N4)C=C5C=CC(=N5)C=C1N2
|
gptkbp:isSolubleIn
|
gptkb:water
organic solvents
|
gptkbp:isSynthesizedBy
|
Adler-Longo method
Rothemund reaction
|
gptkbp:IUPACName
|
hemoglobin
|
gptkbp:ligand
|
hemoglobin
|
gptkbp:location
|
erythrocyte cytoplasm
|
gptkbp:measures
|
hemoglobin test
|
gptkbp:meltingPoint
|
>300°C
|
gptkbp:molecularWeight
|
~64,500 Da
310.35 g/mol
|
gptkbp:namedAfter
|
Greek word 'porphyra' (purple)
|
gptkbp:PDB
|
1A3N
|
gptkbp:predecessor
|
hemoglobin
vitamin B12
Chlorophyll
|
gptkbp:relatedTo
|
porphyria
metalloporphyrin
|
gptkbp:sensitivity
|
oxygen
light
|
gptkbp:studiedIn
|
gptkb:medicine
biochemistry
materials science
organic chemistry
|
gptkbp:subjectOf
|
gptkb:Bohr_effect
gptkb:Haldane_effect
gptkb:Glycated_hemoglobin
gptkb:Hemoglobin_electrophoresis
gptkb:Hemoglobinuria
gptkb:Methemoglobinemia
gptkb:Hill_equation
hemoglobin
Hemoglobin function
Hemoglobin measurement
Hemoglobin structure
Hemolysis
oxygen dissociation curve
|
gptkbp:subunit
|
gptkb:alpha_globin
gptkb:beta_globin
|
gptkbp:UniProtID
|
P68871
P69905
|
gptkbp:usedIn
|
gptkb:molecular_electronics
gptkb:photodynamic_therapy
catalysis
dye-sensitized solar cells
|
gptkbp:bfsParent
|
gptkb:protein
|
gptkbp:bfsLayer
|
4
|