gptkbp:instanceOf
|
gptkb:drug
muscle relaxant
|
gptkbp:approvedBy
|
1996 (US)
|
gptkbp:ATCCode
|
gptkb:M03BX02
|
gptkbp:availableOn
|
gptkb:tablet
capsule
|
gptkbp:brand
|
gptkb:Sirdalud
gptkb:Zanaflex
|
gptkbp:CASNumber
|
51322-75-9
|
gptkbp:category
|
centrally acting muscle relaxant
imidazoline derivative
|
gptkbp:chemicalFormula
|
C9H8ClN5S
|
gptkbp:contraindication
|
severe liver impairment
concomitant use with ciprofloxacin
concomitant use with fluvoxamine
|
gptkbp:discoveredBy
|
gptkb:Sandoz
|
gptkbp:eliminationHalfLife
|
2.5 hours
|
https://www.w3.org/2000/01/rdf-schema#label
|
tizanidine
|
gptkbp:interactsWith
|
gptkb:beer
CYP1A2 inhibitors
oral contraceptives
antihypertensive drugs
|
gptkbp:legalStatus
|
prescription only
|
gptkbp:mechanismOfAction
|
alpha-2 adrenergic agonist
|
gptkbp:metabolism
|
liver
|
gptkbp:origin
|
gptkb:Switzerland
|
gptkbp:patentExpired
|
Yes
|
gptkbp:pregnancyCategory
|
C (US)
|
gptkbp:PubChem_CID
|
5487
DB00697
|
gptkbp:routeOfAdministration
|
oral
|
gptkbp:sideEffect
|
dizziness
drowsiness
hypotension
dry mouth
liver dysfunction
weakness
|
gptkbp:UNII
|
6ZDQ3P0S1W
|
gptkbp:usedFor
|
multiple sclerosis
spinal cord injury
muscle spasticity
|
gptkbp:bfsParent
|
gptkb:Muscle_Relaxants,_Central
|
gptkbp:bfsLayer
|
7
|