|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Gastric_cancer
|
|
gptkbp:biologicalProcess
|
signal transduction
GTP binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
1982
|
|
gptkbp:domain
|
gptkb:GTP-binding_domain
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000256078
3265
|
|
gptkbp:enzymeClassification
|
gptkb:EC_3.6.5.2
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:family
|
gptkb:Ras_family
|
|
gptkbp:function
|
gptkb:Signal_transduction
GTPase activity
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01130
|
|
gptkbp:InterPro
|
gptkb:IPR001806
|
|
gptkbp:KEGGID
|
gptkb:hsa:3265
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:G12V
gptkb:G13D
gptkb:Q61L
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Hras
gptkb:rat_Hras
|
|
gptkbp:PDB
|
gptkb:5P21
1AA9
3K8Y
|
|
gptkbp:postTranslationalModification
|
Farnesylation
Palmitoylation
|
|
gptkbp:protein_name
|
gptkb:GTPase_HRas
|
|
gptkbp:proteinFamily
|
gptkb:PF00071
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:RefSeq
|
gptkb:NP_005334.1
|
|
gptkbp:sequence
|
189
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
gptkb:Cytoplasm
|
|
gptkbp:UniGene
|
Hs.654682
|
|
gptkbp:UniProtID
|
gptkb:P01130
|
|
gptkbp:bfsParent
|
gptkb:LDL_receptor
|
|
gptkbp:bfsLayer
|
6
|