|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:cancer
hypertension
|
|
gptkbp:biologicalProcess
|
protein ubiquitination
ubiquitin-protein transferase activity
regulation of protein stability
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
Harvey F. Lodish
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:domain
|
gptkb:WW_domain
gptkb:HECT_domain
C2 domain
|
|
gptkbp:encodedBy
|
gptkb:NEDD4_gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000133119
|
|
gptkbp:fullName
|
Neural precursor cell expressed developmentally down-regulated protein 4
|
|
gptkbp:function
|
gptkb:E3_ubiquitin-protein_ligase
|
|
gptkbp:gene
|
gptkb:NEDD4
|
|
gptkbp:HGNC_ID
|
7727
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Nedd4
|
|
gptkbp:interactsWith
|
gptkb:AKT1
gptkb:SMAD2
gptkb:PTEN
gptkb:ENaC
|
|
gptkbp:location
|
chromosome 15q21.3
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:regulates
|
cell signaling
protein degradation
|
|
gptkbp:UniProtID
|
P46934
|
|
gptkbp:bfsParent
|
gptkb:NEDD4-1
|
|
gptkbp:bfsLayer
|
6
|