epidermal growth factor (EGF)
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
growth factor |
| gptkbp:alternativeName |
gptkb:urogastrone
|
| gptkbp:binds |
gptkb:epidermal_growth_factor_receptor_(EGFR)
|
| gptkbp:discoveredBy |
gptkb:Stanley_Cohen
|
| gptkbp:discoveredIn |
1962
|
| gptkbp:foundIn |
humans
mice other mammals |
| gptkbp:function |
stimulates cell growth
stimulates cell proliferation stimulates cell differentiation |
| gptkbp:gene |
gptkb:EGF_gene
|
| https://www.w3.org/2000/01/rdf-schema#label |
epidermal growth factor (EGF)
|
| gptkbp:locatedOnChromosome |
chromosome 4q25-q27 (human)
|
| gptkbp:medicalUse |
wound healing
treatment of burns |
| gptkbp:NobelPrizeYear |
Stanley Cohen (Nobel Prize in Physiology or Medicine, 1986)
|
| gptkbp:PDB |
gptkb:1EGF
|
| gptkbp:relatedTo |
gptkb:EGFR_signaling_pathway
cancer biology cell signaling |
| gptkbp:sequence |
53 amino acids (human)
|
| gptkbp:structure |
single-chain polypeptide
|
| gptkbp:UniProtID |
P01133
|
| gptkbp:bfsParent |
gptkb:NP_005334.1
|
| gptkbp:bfsLayer |
6
|