Mitogen-activated protein kinase kinase 7

URI: https://gptkb.org/entity/Mitogen-activated_protein_kinase_kinase_7
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:MKK7
gptkb:MAP2K7
gptkb:JNKK2
gptkbp:biologicalProcess apoptotic process
protein serine/threonine kinase activity
cellular response to stress
gptkbp:cellularComponent gptkb:nucleus
gptkb:cytoplasm
gptkbp:discoveredIn 1997
gptkbp:EC_number 2.7.12.2
gptkbp:encodedBy gptkb:MAP2K7_gene
gptkbp:Entrez_Gene_ID 5609
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function phosphorylates and activates JNK MAP kinases
gptkbp:hasRefSeqID NM_145109
gptkbp:HGNC_ID 6841
https://www.w3.org/2000/01/rdf-schema#label Mitogen-activated protein kinase kinase 7
gptkbp:involvedIn gptkb:MAPK_signaling_pathway
stress-activated protein kinase signaling cascade
gptkbp:isKinaseFor gptkb:JNK1
gptkb:JNK2
gptkb:JNK3
gptkbp:locatedOnChromosome gptkb:19p13.2
gptkbp:PDB 2DYL
gptkbp:phosphorylates gptkb:MAPK10
gptkb:MAPK9
gptkb:MAPK8
gptkbp:regulates gptkb:JNK_pathway
gptkbp:UniProtID gptkb:O14733
gptkbp:bfsParent gptkb:MKK7
gptkbp:bfsLayer 7