|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:MKK7
gptkb:MAP2K7
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammatory diseases
|
|
gptkbp:discoveredBy
|
Dérijard et al.
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
gptkb:Mitogen-activated_protein_kinase_kinase_7
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000105379
5609
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
activates JNK pathway
phosphorylates MAPK10/JNK3
phosphorylates MAPK8/JNK1
phosphorylates MAPK9/JNK2
|
|
gptkbp:HGNC_ID
|
6841
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
JNKK2
|
|
gptkbp:interactsWith
|
gptkb:MAPK10
gptkb:MAPK9
gptkb:MAP3K1
gptkb:MAPK8
gptkb:MAP3K2
gptkb:MAP3K7
|
|
gptkbp:involvedIn
|
apoptosis regulation
cellular response to cytokines
stress-activated protein kinase signaling
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
|
gptkbp:OMIM
|
603165
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:phosphorylates
|
gptkb:Ser271
gptkb:Thr275
|
|
gptkbp:product
|
MAP2K7 protein
|
|
gptkbp:UniProtID
|
gptkb:O14733
|
|
gptkbp:bfsParent
|
gptkb:MKK7
|
|
gptkbp:bfsLayer
|
7
|