Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:MAP2K3
gptkb:Mitogen-activated_protein_kinase_kinase_3 |
| gptkbp:associatedWith |
gptkb:cancer
inflammatory diseases |
| gptkbp:biologicalProcess |
signal transduction
apoptosis regulation protein serine/threonine kinase activity cellular response to stress |
| gptkbp:EC_number |
2.7.12.2
|
| gptkbp:encodedBy |
gptkb:MAP2K3_gene
|
| gptkbp:function |
phosphorylates and activates p38 MAP kinase
involved in stress-activated protein kinase signaling pathway |
| https://www.w3.org/2000/01/rdf-schema#label |
MEK3
|
| gptkbp:locatedOnChromosome |
gptkb:17q11.2
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:MAPK11
gptkb:MAPK12 gptkb:MAPK13 gptkb:MAPK14 |
| gptkbp:regulates |
activated by phosphorylation
regulated by upstream kinases such as MAP3K |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:UniProtID |
gptkb:P46734
|
| gptkbp:bfsParent |
gptkb:MAP2K3
gptkb:MKK3 |
| gptkbp:bfsLayer |
7
|