Mitogen-activated protein kinase kinase 3
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:MEK3
MAPKK3 |
| gptkbp:biologicalProcess |
signal transduction
protein serine/threonine kinase activity cellular response to stress |
| gptkbp:Entrez_Gene_ID |
GC17M042234
|
| gptkbp:enzymeCommissionNumber |
2.7.12.2
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
phosphorylates and activates p38 MAP kinase
|
| gptkbp:gene |
gptkb:MAP2K3
|
| gptkbp:HGNC_ID |
6847
|
| https://www.w3.org/2000/01/rdf-schema#label |
Mitogen-activated protein kinase kinase 3
|
| gptkbp:involves |
immune response
inflammatory response |
| gptkbp:locatedIn |
gptkb:Homo_sapiens
|
| gptkbp:locatedOnChromosome |
17q11.2-q12
|
| gptkbp:OMIM |
603166
|
| gptkbp:part_of_pathway |
gptkb:MAPK_signaling_pathway
|
| gptkbp:phosphorylates |
gptkb:MAP3K
|
| gptkbp:RefSeq |
NM_002756
|
| gptkbp:regulates |
apoptosis
cell proliferation differentiation |
| gptkbp:substrate |
gptkb:MAPK11
gptkb:MAPK12 gptkb:MAPK13 gptkb:MAPK14 |
| gptkbp:UniProtID |
Q02750
|
| gptkbp:bfsParent |
gptkb:MAP2K3
gptkb:MKK3 |
| gptkbp:bfsLayer |
7
|