Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:MAP_kinase_kinase_(MAP2K)
dual phosphorylation |
| gptkbp:alsoKnownAs |
gptkb:Mitogen-activated_protein_kinase
|
| gptkbp:contains |
gptkb:JNK
gptkb:p38_MAPK gptkb:ERK |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
MAPK genes
|
| gptkbp:enzymeCommissionNumber |
gptkb:EC_2.7.11.24
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylates target proteins
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP kinase (MAPK)
|
| gptkbp:inhibitedBy |
MAP kinase phosphatase
|
| gptkbp:involvedIn |
apoptosis
cell differentiation cell proliferation cell signaling stress response |
| gptkbp:phosphorylates |
serine/threonine residues
|
| gptkbp:regulates |
cell survival
gene expression immune response cytoskeletal rearrangement |
| gptkbp:relatedTo |
signaling molecule
|
| gptkbp:studiedIn |
cancer research
immunology neuroscience |
| gptkbp:superfamily |
gptkb:protein_kinase_superfamily
|
| gptkbp:bfsParent |
gptkb:MAP_kinase_kinase_(MAP2K)
gptkb:MAP_kinase_kinase_kinase |
| gptkbp:bfsLayer |
7
|