Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
signaling molecule
|
| gptkbp:activatedBy |
stress
cytokines growth factors |
| gptkbp:alsoKnownAs |
gptkb:Mitogen-activated_protein_kinase_pathway
|
| gptkbp:component |
gptkb:ERK_pathway
gptkb:JNK_pathway gptkb:p38_MAPK_pathway |
| gptkbp:downstreamOf |
transcription factors
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:firstDescribed |
1990s
|
| gptkbp:foundIn |
eukaryotes
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP kinase pathway
|
| gptkbp:involves |
gptkb:MAP_kinase_kinase
gptkb:MAP_kinase_kinase_kinase MAP kinase |
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation cell survival gene expression |
| gptkbp:studiedIn |
cancer research
molecular biology |
| gptkbp:target |
therapeutic drugs
|
| gptkbp:upregulatedBy |
gptkb:Ras_protein
|
| gptkbp:bfsParent |
gptkb:G_protein-coupled_receptor
|
| gptkbp:bfsLayer |
5
|