Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:MAP_kinase_kinase_kinase_(MAP3K)
|
| gptkbp:alsoKnownAs |
gptkb:MEK
gptkb:MAP2K |
| gptkbp:contains |
serine/threonine protein kinase domain
|
| gptkbp:enzymeClassification |
gptkb:EC_2.7.12.2
|
| gptkbp:example |
gptkb:MEK1
gptkb:MEK2 gptkb:MKK3 gptkb:MKK4 gptkb:MKK6 gptkb:MKK7 gptkb:MKK5 MKK9 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylates MAP kinase
|
| gptkbp:inhibitedBy |
gptkb:MEK_inhibitors
|
| gptkbp:involvedIn |
gptkb:MAPK_signaling_pathway
|
| gptkbp:phosphorylates |
serine
threonine |
| gptkbp:proteinFamily |
gptkb:MAP2K_family
|
| gptkbp:regulates |
phosphorylation
protein-protein interaction |
| gptkbp:role |
apoptosis
cell differentiation cell proliferation oncogenesis stress response |
| gptkbp:structure |
dimer
|
| gptkbp:substrate |
gptkb:MAP_kinase
|
| gptkbp:bfsParent |
gptkb:MAPK_pathway
gptkb:MAP_kinase_pathway |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP kinase kinase
|