|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:PRAK
MK5
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
inflammatory bowel disease
|
|
gptkbp:discoveredBy
|
2002
|
|
gptkbp:Entrez_Gene_ID
|
11014
ENSG00000135341
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:kidney
brain
heart
liver
|
|
gptkbp:fullName
|
Mitogen-activated protein kinase-activated protein kinase 25
|
|
gptkbp:function
|
regulation of apoptosis
serine/threonine-protein kinase activity
regulation of inflammation
involved in stress-activated signaling pathways
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:MAPKAPK25
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPKAPK25
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:HSP27
gptkb:p38_MAPK
gptkb:ERK3
gptkb:ERK4
|
|
gptkbp:locatedOnChromosome
|
12q24.12
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mapkapk5
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
stress response pathway
|
|
gptkbp:phosphorylates
|
gptkb:Bcl-2
gptkb:HSP27
gptkb:p53
gptkb:ERK3
gptkb:ERK4
gptkb:p38_MAP_kinase
ASK1
FoxO3
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
cell survival
cell migration
inflammatory response
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9H2S6
|
|
gptkbp:bfsParent
|
gptkb:RAF1_gene
|
|
gptkbp:bfsLayer
|
7
|