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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:HSPB1
gptkb:Heat_shock_protein_beta-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
cardiovascular diseases
|
|
gptkbp:clinicalBiomarker
|
stress
cancer prognosis
|
|
gptkbp:discoveredBy
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:HSPB1_gene
|
|
gptkbp:function
|
regulates apoptosis
chaperone activity
involved in cytoskeletal organization
involved in stress response
prevents aggregation of denatured proteins
|
|
gptkbp:gene
|
gptkb:HSPB1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HSP27
|
|
gptkbp:interactsWith
|
gptkb:actin
tubulin
other heat shock proteins
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
extracellular space
|
|
gptkbp:locatedOnChromosome
|
7q11.23
|
|
gptkbp:molecularWeight
|
27 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Charcot-Marie-Tooth_disease_type_2F
gptkb:distal_hereditary_motor_neuropathy_type_II
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:structure
|
forms oligomers
|
|
gptkbp:UniProtID
|
gptkb:P04792
|
|
gptkbp:bfsParent
|
gptkb:p38_MAPK_pathway
|
|
gptkbp:bfsLayer
|
6
|