|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
gptkb:MEK1
gptkb:MEK2
|
|
gptkbp:alternativeName
|
gptkb:ERK1
gptkb:Extracellular_signal-regulated_kinase_1
gptkb:MAP_kinase_2
|
|
gptkbp:associatedWith
|
gptkb:cancer
cellular stress response
|
|
gptkbp:encodes
|
Mitogen-activated protein kinase 2
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000100030
5594
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
regulation of cell proliferation
regulation of transcription
regulation of differentiation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6871
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK2
|
|
gptkbp:inhibitedBy
|
gptkb:MAPK_phosphatases
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17
|
|
gptkbp:memberOf
|
gptkb:MAP_kinase_family
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
transcription factors
other kinases
|
|
gptkbp:regulates
|
apoptosis
cell cycle
cellular response to growth factors
|
|
gptkbp:structure
|
serine/threonine kinase domain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P28482
|
|
gptkbp:bfsParent
|
gptkb:MAPK1_gene
|
|
gptkbp:bfsLayer
|
7
|