Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:associatedWith |
immune response
cytokine receptor signaling |
| gptkbp:discoveredIn |
1992
|
| gptkbp:encodedBy |
gptkb:JAK1_gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000162434
|
| gptkbp:fullName |
gptkb:Janus_kinase_1
|
| gptkbp:function |
signal transduction
tyrosine kinase activity |
| gptkbp:HGNC_ID |
6190
|
| https://www.w3.org/2000/01/rdf-schema#label |
Jak1
|
| gptkbp:interactsWith |
gptkb:STAT1
gptkb:IFNGR1 gptkb:STAT3 gptkb:IL6ST |
| gptkbp:involvedIn |
gptkb:JAK-STAT_signaling_pathway
|
| gptkbp:locatedOnChromosome |
1p31.3
|
| gptkbp:memberOf |
gptkb:Janus_kinase_family
|
| gptkbp:mutationAssociatedWith |
immunodeficiency
autoinflammatory diseases |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:target |
gptkb:ruxolitinib
gptkb:tofacitinib gptkb:baricitinib |
| gptkbp:UniProtID |
gptkb:P23458
|
| gptkbp:bfsParent |
gptkb:JAK1
|
| gptkbp:bfsLayer |
8
|