|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:immune_response
cytokine receptor signaling
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodedBy
|
gptkb:JAK1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000162434
|
|
gptkbp:fullName
|
gptkb:Janus_kinase_1
|
|
gptkbp:function
|
signal transduction
tyrosine kinase activity
|
|
gptkbp:HGNC_ID
|
6190
|
|
gptkbp:interactsWith
|
gptkb:STAT1
gptkb:IFNGR1
gptkb:STAT3
gptkb:IL6ST
|
|
gptkbp:involvedIn
|
gptkb:JAK-STAT_signaling_pathway
|
|
gptkbp:locatedOnChromosome
|
1p31.3
|
|
gptkbp:memberOf
|
gptkb:Janus_kinase_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:immunodeficiency
autoinflammatory diseases
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:target
|
gptkb:ruxolitinib
gptkb:tofacitinib
gptkb:baricitinib
|
|
gptkbp:UniProtID
|
gptkb:P23458
|
|
gptkbp:bfsParent
|
gptkb:JAK1
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Jak1
|