Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases |
| gptkbp:composedOf |
gptkb:JAK2
gptkb:JAK1 gptkb:TYK2 gptkb:JAK3 |
| gptkbp:discoveredBy |
gptkb:Darnell_JE_Jr.
|
| gptkbp:domain |
kinase domain
pseudokinase domain |
| gptkbp:enzymeClassification |
EC 2.7.10.2
|
| gptkbp:function |
signal transduction
cytokine receptor signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
Janus kinase family
|
| gptkbp:involvedIn |
gptkb:JAK-STAT_signaling_pathway
|
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:memberOf |
tyrosine kinase family
|
| gptkbp:namedAfter |
Janus (Roman god)
|
| gptkbp:phosphorylates |
gptkb:STAT_proteins
|
| gptkbp:regulates |
gene expression
|
| gptkbp:target |
JAK inhibitors
|
| gptkbp:bfsParent |
gptkb:JAK2
gptkb:JAK3 |
| gptkbp:bfsLayer |
7
|