|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:MGC11228
gptkb:BZS
gptkb:MGC11227
gptkb:MHAM
gptkb:MMAC1
gptkb:PTEN1
gptkb:TEP1
|
|
gptkbp:approvalYear
|
1997-05-19
|
|
gptkbp:approvedBy
|
gptkb:phosphatase_and_tensin_homolog
|
|
gptkbp:approvedSymbol
|
gptkb:PTEN
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:endometrial_cancer
gptkb:glioblastoma
melanoma
prostate cancer
|
|
gptkbp:dateModified
|
2022-03-10
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171862
5728
|
|
gptkbp:externalLink
|
https://www.ncbi.nlm.nih.gov/gene/5728
https://www.uniprot.org/uniprot/P60484
https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9967
|
|
gptkbp:function
|
gptkb:protein
tumor suppressor
lipid phosphatase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:9967
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:9967
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:10q23.31
|
|
gptkbp:locusType
|
gene with protein product
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Pten
gptkb:zebrafish_ptena
gptkb:zebrafish_ptenb
rat Pten
|
|
gptkbp:pathway
|
gptkb:PI3K-Akt_signaling_pathway
apoptosis
cell proliferation
cell cycle regulation
cell migration
|
|
gptkbp:proteinFamily
|
phosphatases
tumor suppressors
|
|
gptkbp:RefSeq
|
gptkb:NM_000314
|
|
gptkbp:status
|
Approved
|
|
gptkbp:symbol
|
gptkb:PTEN
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:RET_proto-oncogene
|
|
gptkbp:bfsLayer
|
5
|