Statements (68)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:disease
|
| gptkbp:acquired_by |
histopathological examination
|
| gptkbp:affects |
cerebellum
|
| gptkbp:can_be_symptomatic_or_asymptomatic |
gptkb:true
|
| gptkbp:can_be_used_to |
vision problems
ataxia speech difficulties |
| gptkbp:can_cause |
fatigue
nausea seizures tremors |
| gptkbp:can_involve |
multifocal lesions
|
| gptkbp:can_lead_to |
social challenges
headaches balance issues emotional disturbances |
| gptkbp:can_result_in |
cognitive impairment
|
| gptkbp:descendant |
gptkb:true
|
| gptkbp:diagnosis |
clinical evaluation
neurological assessment MRI scan adolescents and adults |
| gptkbp:exhibits |
motor skill difficulties
|
| gptkbp:first_described_by |
gptkb:1963
|
| gptkbp:has_achieved |
gptkb:Figaro
|
| https://www.w3.org/2000/01/rdf-schema#label |
Lhermitte-Duclos disease
|
| gptkbp:is_a_condition_that_affects |
young adults
|
| gptkbp:is_a_rare_condition_that_affects |
brain function
|
| gptkbp:is_a_rare_genetic_disorder |
gptkb:true
|
| gptkbp:is_associated_with |
gptkb:Cowden_syndrome
mental health issues skin lesions gastrointestinal polyps thyroid cancer risk other tumors breast cancer risk endometrial cancer risk |
| gptkbp:is_characterized_by |
cerebellar dysfunction
abnormal cerebellar architecture cerebellar enlargement cerebellar symptoms cerebellar dysplastic gangliocytoma abnormal neuronal growth |
| gptkbp:is_common_in |
adults
|
| gptkbp:is_linked_to |
gptkb:PTEN_hamartoma_tumor_syndrome
increased cancer risk |
| gptkbp:is_linked_to_mutations_in |
gptkb:PTEN_gene
|
| gptkbp:is_monitored_by |
regular imaging studies
|
| gptkbp:is_often_seen_in |
other brain tumors
|
| gptkbp:is_part_of |
Cowden syndrome spectrum
|
| gptkbp:is_part_of_the_differential_diagnosis_for |
cerebellar lesions
|
| gptkbp:named_after |
Jacques Lhermitte
Pierre Duclos |
| gptkbp:rarity |
gptkb:true
|
| gptkbp:requires |
genetic counseling
rehabilitation therapy long-term follow-up neurological evaluation |
| gptkbp:scientific_classification |
neurocutaneous syndrome
|
| gptkbp:treatment |
gptkb:surgery
radiation therapy neurosurgeons medications for symptoms |
| gptkbp:type_of |
gptkb:Oncology
cerebellar tumor |
| gptkbp:was_a_result_of |
abnormal cell growth
|
| gptkbp:bfsParent |
gptkb:PTEN
|
| gptkbp:bfsLayer |
5
|