|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:biologicalProcess
|
protein tyrosine phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:Entrez_Gene_ID
|
19211
ENSMUSG00000027250
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
brain
heart
liver
|
|
gptkbp:fullName
|
gptkb:phosphatase_and_tensin_homolog
|
|
gptkbp:function
|
gptkb:tumor_suppressor
gptkb:protein
lipid phosphatase
|
|
gptkbp:gene
|
Pten
|
|
gptkbp:involvedIn
|
gptkb:PI3K/AKT_signaling_pathway
embryonic development
cell migration
apoptosis regulation
cell proliferation regulation
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
|
gptkbp:mutationAssociatedWith
|
macrocephaly
impaired neuronal migration
increased tumorigenesis
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
gptkb:human_PTEN
|
|
gptkbp:regulates
|
gptkb:immune_response
gptkb:synaptic_plasticity
cell survival
DNA repair
cellular senescence
angiogenesis
glucose metabolism
cell cycle
neurogenesis
myelination
autophagy
cell polarity
hematopoiesis
epithelial-mesenchymal transition
axon guidance
cell size
stem cell self-renewal
|
|
gptkbp:UniProtID
|
O08586
|
|
gptkbp:bfsParent
|
gptkb:HGNC:11368
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mouse Pten
|