Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:biologicalProcess |
protein tyrosine phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity |
| gptkbp:cellularComponent |
gptkb:nucleus
gptkb:cytoplasm gptkb:plasma_membrane |
| gptkbp:Entrez_Gene_ID |
19211
ENSMUSG00000027250 |
| gptkbp:expressedIn |
gptkb:cancer
gptkb:kidney gptkb:testis brain heart liver |
| gptkbp:fullName |
gptkb:phosphatase_and_tensin_homolog
|
| gptkbp:function |
gptkb:protein
tumor suppressor lipid phosphatase |
| gptkbp:gene |
Pten
|
| https://www.w3.org/2000/01/rdf-schema#label |
mouse Pten
|
| gptkbp:involvedIn |
gptkb:PI3K/AKT_signaling_pathway
embryonic development cell migration apoptosis regulation cell proliferation regulation |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
|
| gptkbp:mutationAssociatedWith |
macrocephaly
impaired neuronal migration increased tumorigenesis |
| gptkbp:organism |
gptkb:Mus_musculus
|
| gptkbp:orthologIn |
gptkb:human_PTEN
|
| gptkbp:regulates |
gptkb:synaptic_plasticity
cell survival DNA repair cellular senescence angiogenesis glucose metabolism immune response cell cycle neurogenesis myelination autophagy cell polarity hematopoiesis epithelial-mesenchymal transition axon guidance cell size stem cell self-renewal |
| gptkbp:UniProtID |
O08586
|
| gptkbp:bfsParent |
gptkb:HGNC:9967
|
| gptkbp:bfsLayer |
6
|