|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:GATA-2
gptkb:GATA-binding_factor_2
gptkb:NFE1B
|
|
gptkbp:associatedWith
|
gptkb:acute_myeloid_leukemia
gptkb:Emberger_syndrome
gptkb:MonoMAC_syndrome
immunodeficiency
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:domain
|
zinc finger
|
|
gptkbp:Entrez_Gene_ID
|
2624
ENSG00000179348
|
|
gptkbp:expressedIn
|
endothelial cells
hematopoietic stem cells
|
|
gptkbp:fullName
|
gptkb:GATA_binding_protein_2
|
|
gptkbp:function
|
transcription factor
regulation of hematopoiesis
regulation of endothelial cell biology
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
4171
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Gata2
|
|
gptkbp:length
|
480
|
|
gptkbp:locatedOnChromosome
|
3
|
|
gptkbp:location
|
3q21.3
|
|
gptkbp:molecularWeight
|
50 kDa
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
predisposition to leukemia
|
|
gptkbp:OMIM
|
137295
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Gata2 (Mus musculus)
|
|
gptkbp:proteinFamily
|
gptkb:GATA_family
|
|
gptkbp:RefSeq
|
NM_001145661
NP_001139133
|
|
gptkbp:regulates
|
gptkb:GATA1
gptkb:LMO2
gptkb:CD34
gptkb:FLT3
gptkb:c-KIT
gptkb:EPO
gptkb:MPL
gptkb:RUNX1
gptkb:PU.1
cell differentiation
cell proliferation
cell survival
IL7R
SCL/TAL1
|
|
gptkbp:transcription_factor_class
|
zinc finger
|
|
gptkbp:transcription_regulation
|
binds GATA consensus sequence
|
|
gptkbp:UniProtID
|
P23769
|
|
gptkbp:bfsParent
|
gptkb:GATA2
|
|
gptkbp:bfsLayer
|
7
|