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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
STEP
|
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gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:fragile_X_syndrome
schizophrenia
|
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gptkbp:biologicalProcess
|
learning and memory
protein tyrosine phosphatase activity
negative regulation of synaptic transmission
|
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gptkbp:discoveredBy
|
gptkb:Paul_Lombroso
|
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gptkbp:encodes
|
gptkb:protein_tyrosine_phosphatase,_non-receptor_type_5
|
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gptkbp:Entrez_Gene_ID
|
5771
ENSG00000135341
|
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gptkbp:expressedIn
|
brain
|
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gptkbp:firstDescribed
|
1993
|
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gptkbp:function
|
dephosphorylation of MAP kinases
regulation of synaptic plasticity
|
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gptkbp:geneType
|
protein-coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPN5
|
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gptkbp:locatedOnChromosome
|
chromosome 11
11q13.1
|
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gptkbp:OMIM
|
600579
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
gptkb:Ptpn5
|
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gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase_family
|
|
gptkbp:regulates
|
gptkb:ERK1/2
gptkb:AMPA_receptor
gptkb:NMDA_receptor
gptkb:Fyn_kinase
|
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gptkbp:UniProtID
|
Q12923
|
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gptkbp:bfsParent
|
gptkb:protein_tyrosine_phosphatases
|
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gptkbp:bfsLayer
|
6
|