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gptkbp:instanceOf
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MeSH Unique Identifier
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https://www.w3.org/2000/01/rdf-schema#label
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D010141
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gptkbp:MeSH_Concept
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gptkb:Parkinson_Disease
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gptkbp:MeSH_Date_Established
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1966
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gptkbp:MeSH_ID
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gptkb:D010141
gptkb:Idiopathic_Parkinsonism
gptkb:Paralysis_Agitans
gptkb:Parkinson_Disease
gptkb:Parkinsonism,_Idiopathic
gptkb:Parkinsonism,_Primary
gptkb:Shaking_Palsy
gptkb:Primary_Parkinsonism
gptkb:Parkinson's_Disease
A progressive, degenerative neurologic disease characterized by tremor, muscular rigidity, and slow, imprecise movement, chiefly affecting middle-aged and elderly people. It is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine.
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gptkbp:MeSH_tree_number
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C10.228.140.546.450
C20.111.258.625.500
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gptkbp:refersTo
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gptkb:Parkinson_Disease
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gptkbp:relatedTo
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gptkb:Aging
gptkb:LRRK2
gptkb:SNCA
gptkb:dementia
gptkb:Alpha-synuclein
gptkb:Basal_Ganglia_Diseases
gptkb:Deep_Brain_Stimulation
gptkb:Dopamine_Deficiency
gptkb:Dopaminergic_Agents
gptkb:Drug-Induced_Parkinsonism
gptkb:Freezing_of_Gait
gptkb:Lewy_Bodies
gptkb:Movement_Disorders
gptkb:Neurodegenerative_Diseases
gptkb:Parkin_(PARK2)
gptkb:Parkinson_Disease,_Drug-Induced
gptkb:Parkinson_Disease,_Hereditary
gptkb:Parkinson_Disease,_Juvenile
gptkb:Parkinson_Disease,_Postencephalitic
gptkb:Parkinson_Disease,_Posttraumatic
gptkb:Parkinson_Disease,_Secondary
gptkb:Parkinson_Disease,_Vascular
gptkb:Substantia_Nigra
gptkb:Ubiquitin-Proteasome_System
gptkb:Parkinsonism
gptkb:Corticobasal_Degeneration
gptkb:Dementia_with_Lewy_Bodies
gptkb:Multiple_System_Atrophy
gptkb:Progressive_Supranuclear_Palsy
gptkb:DJ-1
gptkb:PINK1
gptkb:Psychosis
gptkb:Levodopa
gptkb:Hallucinations
gptkb:Micrographia
gptkb:Tremor
gptkb:REM_Sleep_Behavior_Disorder
Depression
Constipation
Rigidity
Sleep Disorders
Atypical Parkinsonism
Bradykinesia
Secondary Parkinsonism
Akinesia
Autonomic Dysfunction
Cogwheel Rigidity
Dopaminergic Neurons
Dyskinesias
Environmental Risk Factors
Extrapyramidal Disorders
Festinating Gait
Gait Disturbance
Genetic Predisposition to Disease
Hypokinesia
Idiopathic Disease
Masked Facies
Mitochondrial Dysfunction
Motor Symptoms
Neurodegeneration
Neuroinflammation
Neuroprotection
Neurotransmitter Disorders
Non-motor Symptoms
Olfactory Dysfunction
On-Off Phenomenon
Oxidative Stress
Pill-rolling Tremor
Postural Instability
Progressive Disease
Protein Aggregation
Resting Tremor
Shuffling Gait
Speech Disorders
Stooped Posture
Urinary Dysfunction
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gptkbp:bfsParent
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gptkb:Paget's_disease_of_the_breast
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gptkbp:bfsLayer
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6
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