Dementia with Lewy Bodies

URI: https://gptkb.org/entity/Dementia_with_Lewy_Bodies
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf neurodegenerative disease
gptkbp:abbreviation gptkb:DLB
gptkbp:causedBy Lewy body accumulation
gptkbp:complication malnutrition
falls
delirium
dysphagia
gptkbp:differentialDiagnosis gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease_dementia
frontotemporal dementia
gptkbp:eponymOf gptkb:Frederic_Lewy
gptkbp:firstDescribed 1912
gptkbp:frequency second most common degenerative dementia after Alzheimer's disease
gptkbp:hasDiagnosticCriteria gptkb:McKeith_criteria
gptkbp:hasDiagnosticTool gptkb:DaTscan
neuropsychological testing
brain MRI
gptkbp:hasLanguage English
gptkbp:hasOrphanetID ORPHA:705
gptkbp:hasRelatedDisorder gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:Multiple_system_atrophy
gptkbp:hasUMLSID C0752342
gptkbp:hasWikipediaPage https://en.wikipedia.org/wiki/Dementia_with_Lewy_bodies
https://www.w3.org/2000/01/rdf-schema#label Dementia with Lewy Bodies
gptkbp:ICD-10_code G31.8
gptkbp:MeSH_ID gptkb:D000544
gptkbp:mortalityRate reduced life expectancy
gptkbp:OMIM 127750
gptkbp:onset gradual
gptkbp:pathology Lewy bodies in cortex and brainstem
alpha-synuclein inclusions
gptkbp:prevalence 0.4% in people over 65
gptkbp:prognosis progressive
gptkbp:riskFactor age
family history
male sex
gptkbp:symptom gptkb:REM_sleep_behavior_disorder
cognitive decline
autonomic dysfunction
fluctuating cognition
parkinsonism
visual hallucinations
gptkbp:treatment occupational therapy
physical therapy
cholinesterase inhibitors
antipsychotics (with caution)
gptkbp:bfsParent gptkb:Atypical_Parkinsonian_Syndromes
gptkbp:bfsLayer 6