Paget's disease of the breast

URI: https://gptkb.org/entity/Paget's_disease_of_the_breast
GPTKB entity
Statements (47)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affects gptkb:breast
gptkbp:alsoKnownAs gptkb:mammary_Paget's_disease
gptkbp:associatedWith underlying ductal carcinoma
gptkbp:cellType gptkb:Paget_cells
gptkbp:complication recurrence
invasive breast cancer
gptkbp:diagnosedBy clinical examination
biopsy
mammography
gptkbp:differentialDiagnosis gptkb:eczema
gptkb:contact_dermatitis
psoriasis
gptkbp:firstDescribed gptkb:Sir_James_Paget
1874
gptkbp:frequency 1-4% of all breast cancers
gptkbp:histology presence of Paget cells in epidermis of nipple
https://www.w3.org/2000/01/rdf-schema#label Paget's disease of the breast
gptkbp:ICD-10_code gptkb:C50.9
gptkbp:MeSH_ID gptkb:D010141
gptkbp:mortalityRate related to underlying carcinoma
gptkbp:namedAfter gptkb:James_Paget
gptkbp:notToBeConfusedWith gptkb:Paget's_disease_of_bone
gptkbp:occurredIn males
gptkbp:Paget_cells intraepithelial adenocarcinoma cells
large cells with clear cytoplasm
gptkbp:prevalence rare
gptkbp:prognosis depends on presence of underlying cancer
gptkbp:riskFactor age
family history of breast cancer
gptkbp:sex female
gptkbp:symptom bleeding
itching
redness
eczema-like changes of the nipple
flaking skin
lump in the breast
nipple discharge
gptkbp:treatment surgery
radiation therapy
chemotherapy
hormone therapy
breast-conserving surgery
mastectomy
gptkbp:bfsParent gptkb:James_Paget
gptkbp:bfsLayer 5