Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:affects |
central nervous system
peripheral nervous system |
| gptkbp:characterizedBy |
progressive loss of structure or function of neurons
|
| gptkbp:commonPathology |
protein misfolding
neuroinflammation neuronal death |
| gptkbp:diagnosedBy |
brain imaging
neurological examination genetic testing |
| gptkbp:field |
Neurology
|
| gptkbp:hasNoCure |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
Neurodegenerative Diseases
|
| gptkbp:impact |
disability
increased mortality reduced quality of life |
| gptkbp:includes |
gptkb:Alzheimer's_disease
gptkb:Amyotrophic_lateral_sclerosis gptkb:Parkinson's_disease gptkb:Frontotemporal_dementia gptkb:Multiple_system_atrophy gptkb:Huntington's_disease |
| gptkbp:prevalence |
increases with age
|
| gptkbp:researchInterest |
biomarkers
disease-modifying therapies genetic factors protein aggregation |
| gptkbp:riskFactor |
age
environmental factors genetic mutations |
| gptkbp:symptom |
behavioral changes
cognitive decline memory loss motor dysfunction |
| gptkbp:treatment |
occupational therapy
physical therapy medications symptomatic therapy |
| gptkbp:bfsParent |
gptkb:D010141
gptkb:Signal_Transduction gptkb:Cell_Communication |
| gptkbp:bfsLayer |
7
|