Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
|
| gptkbp:affects |
central nervous system
|
| gptkbp:alsoKnownAs |
gptkb:Parkinson's_disease
gptkb:Idiopathic_Parkinsonism |
| gptkbp:canBeChronic |
true
|
| gptkbp:causedBy |
unknown
|
| gptkbp:characterizedBy |
loss of dopaminergic neurons in substantia nigra
|
| gptkbp:complication |
gptkb:dementia
gptkb:depression autonomic dysfunction |
| gptkbp:firstDescribed |
gptkb:James_Parkinson
1817 |
| https://www.w3.org/2000/01/rdf-schema#label |
Parkinsonism, Idiopathic
|
| gptkbp:ICD-10_code |
gptkb:G20
|
| gptkbp:inheritance |
sporadic
|
| gptkbp:isProgressive |
true
|
| gptkbp:MeSH_ID |
D010300
|
| gptkbp:OMIM |
168600
|
| gptkbp:onset |
usually after age 60
|
| gptkbp:pathology |
Lewy bodies
|
| gptkbp:prevalence |
more common in men
|
| gptkbp:riskFactor |
age
family history |
| gptkbp:symptom |
bradykinesia
postural instability rigidity tremor |
| gptkbp:treatment |
gptkb:levodopa
MAO-B inhibitors deep brain stimulation dopamine agonists |
| gptkbp:bfsParent |
gptkb:D010141
|
| gptkbp:bfsLayer |
7
|